Thoracic Oncology

Zenocutuzumab administration

  • 1.  Zenocutuzumab administration

    Posted 18 hours ago

    Hi all,

    Has anyone started using zenocutuzumab? There are different recommendations for infusion duration between the eNRGy1 study and FDA approval - eNRGy1 infused over 4 hours for first dose and then dropped to 2 hours for subsequent doses if no IRR Grade > 2, while FDA approved as 4 hours and does not mention reducing the infusion time. It seems reasonable to me to reduce the administration time for subsequent doses given the low rates of IRRs, but I was curious how others have implemented this or if anyone has further insight?

    Thanks in advance!

    Cami



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    Cami Andreini, PharmD, BCOP, CPP
    Duke University Hospital
    cla54@duke.edu
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